Fig. 1 What is in the bottle
- 10AlphaRet. A retinoid and lactic acid (an AHA), joined into one molecule. skinbetter's patented technology.
- 12Peptides. Palmitoyl tripeptide-1 and palmitoyl tetrapeptide-7.
- 14Moisture. Ceramide NP, hyaluronic acid and squalane, to counter the dryness retinoids are known for.
Full ingredient list51
- Aqua/Water
- Sodium Glycolate
- Glycolic Acid
- Cetearyl Olivate
- Pentylene Glycol
- Cyclopentasiloxane
- Isohexadecane
- Sorbitan Olivate
- Tetrahexyldecyl Ascorbate
- Glycerin
- Ceresin
- Glycol Palmitate
- Butylene Glycol
- Niacinamide
- Squalane
- Methyl Gluceth-20
- Ethyl Lactyl Retinoate
- Palmitoyl Tripeptide-1
- Palmitoyl Tetrapeptide-7
- Ceramide NP
- Hyaluronic Acid
- Ubiquinone
- Tocopherol
- Bisabolol
- Tocopheryl Acetate
- Superoxide Dismutase
- Butyrospermum Parkii (Shea) Butter
- Allantoin Glycyrrhetinic Acid
- Sodium PCA
- Panthenol
- Camellia Sinensis Leaf Extract
- Portulaca Oleracea Extract
- Linoleic Acid
- Cholesterol
- Linolenic Acid
- Magnesium Aluminum Silicate
- Dimethyl Isosorbide
- Dimethicone
- Glyceryl Stearate
- PEG-100 Stearate
- Steareth-2
- Hydroxyethylcellulose
- Acacia Senegal Gum
- Xanthan Gum
- Hydrated Silica
- Carbomer
- Polysorbate 20
- Disodium EDTA
- Ethylhexylglycerin
- Phenoxyethanol
- Titanium Dioxide (CI 77891).
As published by skinbetter science. The label on the package you receive is the final word.
Crème de nuit AlphaRet
20x award winner, including Allure Best of Beauty
Improves the appearance of lines, wrinkles, uneven tone and texture.
$145.00
Taille réelle (30 ml)
Renews every 10 weeks until you cancel. Ships free. Skip or cancel anytime.
- Genuine skinbetter product, curated by Holly Tanella. Medical director on staff.
- Free US shipping over $79. Auto Refill ships free at any size.
Fig. 2 Before and after, nightly use
Before4 weeks
skinbetter clinical photography, unretouched, on clean product-free skin. Nightly use. Individual results vary.
Fig. 3 Tested beside prescription tretinoin
33%“33% improvement in the appearance of fine lines and wrinkles in 12 weeks.” Fine lines, 12 wk
14%“14% improvement in hydration in 12 weeks.” Hydration, 12 wk
How this was measured
A 12-week, split-face, randomized, dermatologist-led clinical study in participants with mild-to-severe photoaging (N=48) vs 0.025% tretinoin.
- People
- 48
- Length
- 12 weeks
- Assessed by
- Dermatologist-led
- Source
- skinbetter science
98%“98% of retinoid-sensitive users agree that AlphaRet can be used nightly.” A 12-week multicenter, dermatologist-led clinical study evaluated nightly use of AlphaRet Overnight Cream in participants with self-identified retinoid sensitivity and mild-to-moderate photoaging. (N=56)
Fig. 4 How to use it
EveningSPF 30+ every morning
- À utiliser dans le cadre de votre routine de soins du soir.
- Appliquer une fine couche sur le visage propre et sec. Peut être appliqué sur l'ensemble du visage en évitant le contour des yeux.
- Protégez-vous avec un écran solaire Sunbeam pendant la journée pour des bienfaits supplémentaires en matière de soins de la peau.
AlphaRet is where I start most clients who want to soften the look of lines, uneven tone and texture but have found retinoids too much for their skin before. A thin layer at night on a clean, dry face, avoiding the eyes, and I ask them to give it several weeks before they judge it, because change in how skin looks comes gradually. Sunscreen every morning is part of the deal.
Holly TanellaLicensed esthetician, TX #1612456
Fig. 5 With Even Tone, 12 weeks
AlphaRet Overnight Cream with Even Tone Correcting Serum, 12 weeks. skinbetter clinical photography.
Twenty awards, five of them
- AllureBest of Beauty Breakthrough 2016
- InStyleBest Beauty Buys 2023
- TODAYBeauty Award 2025
- ByrdieSkin Award 2026
- CosmopolitanHoly Grail Hall of Fame 2026
Awards as listed by skinbetter science.
Why buy it here
An authorized skinbetter providerBohemia Skin is the online shop of Boho Med Spa, Holly Tanella's practice. skinbetter only stands behind products bought from its authorized providers, and our medical director is why we can be one.
- Chosen by Holly for the concerns she treats most in her treatment room.
- Not sure which one is right for your skin? Take Holly's skin quiz
- Free US shipping over $79. Auto Refill ships free at any size.
Every
Renews every 10 weeks until you cancel. Ships free. Skip or cancel anytime.